
Turning bystanders
into first responders.
30,000+ units distributed across 50 states
Harm reduction supplies — field tested.
Browse catalogWherever people gather, the ONEbox is ready
From schools to shelters, offices to public parks — the ONEbox adapts to any environment with the same life-saving simplicity.
Trusted by experts.
Used by the leaders.














Meet the ONEbox
A self-contained opioid emergency response station that puts the power of naloxone in anyone's hands. No training required, just pull the tab and follow the on-screen video.

Instant video guidance
Bilingual emergency video activates in 3 seconds. One-minute instructions in English and Spanish walk any bystander through naloxone administration.
3 complete PPE kits
Gloves, CPR shields, and antiseptic wipes. Everything needed to respond safely, packed and ready.
Deploy anywhere
Durable, mountable, and portable. Schools, libraries, offices, public spaces, wherever people gather.
30,000+
Units distributed
50
States covered
500+
Lives saved
Everything you need to save a life, in one box
From the naloxone that reverses an overdose, to the CPR shield that protects the responder, to the video guidance that walks anyone through it — the ONEbox transforms bystanders into first responders.
The response that saves lives
Naloxone is clinically proven to reverse opioid overdoses when administered in time. The ONEbox puts that power in anyone's hands, every time.
Overdose reversal success rate
Up to 93%
From box to naloxone administration
Under 60s
Reduction in overdose fatality risk
Up to 50%
Medical training required to respond
Zero
Driven by purpose. Validated by impact.
We're radically committed to harm reduction, grounded in science, fueled by data, and driven by the belief that everyone deserves access to life-saving tools. Because preparedness is the difference.
Why R3
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Units deployed nationwide

0
States with active deployments

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Lives confirmed saved
Every dot, a life on standby
Schools. Libraries. Workplaces. Public venues. Wherever people gather, R3 stands ready. When an emergency strikes, bystanders pull the tab — and a life gets saved.
30,000 units.
50 states.
Zero hesitation.
From college campuses to community centers, ONEbox stations give anyone the power to respond — no medical training required.
30,000+
Units deployed
50
States
500+
Lives saved
1,200+
Partners
When every degree matters
OSHA-compliant heat emergency training in a box. Bilingual video guidance, complete response kits, and step-by-step protocols — deployable anywhere your teams work.
Hover, focus, or tap the image to open the kit
Turning bystanders into first responders.
Every second matters in an emergency. R3 puts life-saving tools and training into the hands of everyday people — no medical background required. Just open the box and follow the video.
From opioid overdose response to heat emergencies, our kits are designed so anyone can act with confidence when it counts most.
Learn about R3Ready to protect your community?
Whether you need a single unit or a thousand, we'll get life-saving tools into your community fast.


