Turning bystanders
into first responders.

30,000+ units distributed across 50 states

Harm reduction supplies — field tested.

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Wherever people gather, the ONEbox is ready

From schools to shelters, offices to public parks — the ONEbox adapts to any environment with the same life-saving simplicity.

Trusted by experts.
Used by the leaders.

Clemson UniversityDuke UniversityVirginia TechUniversity of GeorgiaElon UniversityCity of NashvilleBloombergBassett Healthcare NetworkFarmingdale State CollegeAPC BirminghamMATTERS NetworkClemson UniversityDuke UniversityVirginia TechUniversity of GeorgiaElon UniversityCity of NashvilleBloombergBassett Healthcare NetworkFarmingdale State CollegeAPC BirminghamMATTERS Network

Meet the ONEbox

A self-contained opioid emergency response station that puts the power of naloxone in anyone's hands. No training required, just pull the tab and follow the on-screen video.

ONEbox Classic with PPE kits
01

Instant video guidance

Bilingual emergency video activates in 3 seconds. One-minute instructions in English and Spanish walk any bystander through naloxone administration.

02

3 complete PPE kits

Gloves, CPR shields, and antiseptic wipes. Everything needed to respond safely, packed and ready.

03

Deploy anywhere

Durable, mountable, and portable. Schools, libraries, offices, public spaces, wherever people gather.

30,000+

Units distributed

50

States covered

500+

Lives saved

Everything you need to save a life, in one box

From the naloxone that reverses an overdose, to the CPR shield that protects the responder, to the video guidance that walks anyone through it — the ONEbox transforms bystanders into first responders.

The response that saves lives

Naloxone is clinically proven to reverse opioid overdoses when administered in time. The ONEbox puts that power in anyone's hands, every time.

Overdose reversal success rate

Up to 93%

From box to naloxone administration

Under 60s

Reduction in overdose fatality risk

Up to 50%

Medical training required to respond

Zero

Driven by purpose. Validated by impact.

We're radically committed to harm reduction, grounded in science, fueled by data, and driven by the belief that everyone deserves access to life-saving tools. Because preparedness is the difference.

Why R3
ONEbox deployed in community setting

0+

Units deployed nationwide

ONEbox co-location installation

0

States with active deployments

ONEbox saving lives

0+

Lives confirmed saved

Every dot, a life on standby

Schools. Libraries. Workplaces. Public venues. Wherever people gather, R3 stands ready. When an emergency strikes, bystanders pull the tab — and a life gets saved.

30,000 units.
50 states.
Zero hesitation.

From college campuses to community centers, ONEbox stations give anyone the power to respond — no medical training required.

30,000+

Units deployed

50

States

500+

Lives saved

1,200+

Partners

When every degree matters

OSHA-compliant heat emergency training in a box. Bilingual video guidance, complete response kits, and step-by-step protocols — deployable anywhere your teams work.

Hover, focus, or tap the image to open the kit

Turning bystanders into first responders.

Every second matters in an emergency. R3 puts life-saving tools and training into the hands of everyday people — no medical background required. Just open the box and follow the video.

From opioid overdose response to heat emergencies, our kits are designed so anyone can act with confidence when it counts most.

Learn about R3

Ready to protect your community?

Whether you need a single unit or a thousand, we'll get life-saving tools into your community fast.